Gemin3
E564272
Gemin3 is an RNA helicase and core component of the SMN complex that plays a crucial role in the assembly and metabolism of small nuclear ribonucleoproteins (snRNPs) involved in pre-mRNA splicing.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Gemin3 canonical | 7 |
| GEM-associated protein 3 | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T6004689 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Gemin3 Context triple: [Survival motor neuron protein, formsComplexWith, Gemin3]
-
A.
Gemin2
Gemin2 is a core component of the SMN complex that plays a crucial role in the assembly of small nuclear ribonucleoproteins (snRNPs) essential for pre-mRNA splicing.
-
B.
Gemin5
Gemin5 is an RNA-binding protein that is part of the SMN complex and plays a key role in small nuclear ribonucleoprotein (snRNP) assembly and pre-mRNA splicing.
-
C.
Gemin6
Gemin6 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins essential for pre-mRNA splicing.
-
D.
Gemini 2.0
Gemini 2.0 is a major updated release of Google’s multimodal AI model family, designed to provide more powerful and versatile capabilities across text, code, image, and other modalities.
-
E.
Gemini SC-4
Gemini SC-4 was the NASA spacecraft used for the Gemini 4 mission, which carried astronauts James McDivitt and Edward White on the first American spacewalk in 1965.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Gemin3 Target entity description: Gemin3 is an RNA helicase and core component of the SMN complex that plays a crucial role in the assembly and metabolism of small nuclear ribonucleoproteins (snRNPs) involved in pre-mRNA splicing.
-
A.
Gemin2
Gemin2 is a core component of the SMN complex that plays a crucial role in the assembly of small nuclear ribonucleoproteins (snRNPs) essential for pre-mRNA splicing.
-
B.
Gemin5
Gemin5 is an RNA-binding protein that is part of the SMN complex and plays a key role in small nuclear ribonucleoprotein (snRNP) assembly and pre-mRNA splicing.
-
C.
Gemin6
Gemin6 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins essential for pre-mRNA splicing.
-
D.
Gemini 2.0
Gemini 2.0 is a major updated release of Google’s multimodal AI model family, designed to provide more powerful and versatile capabilities across text, code, image, and other modalities.
-
E.
Gemini SC-4
Gemini SC-4 was the NASA spacecraft used for the Gemini 4 mission, which carried astronauts James McDivitt and Edward White on the first American spacewalk in 1965.
- F. None of above. chosen
Statements (46)
| Predicate | Object |
|---|---|
| instanceOf |
RNA helicase
ⓘ
protein ⓘ |
| associatedWithDisease | spinal muscular atrophy pathway dysfunction ⓘ |
| associatedWithProcess | neuronal RNA processing ⓘ |
| binds | RNA ⓘ |
| biologicalRole |
core component of SMN complex
ⓘ
facilitates assembly of snRNPs ⓘ participates in pre-mRNA splicing machinery ⓘ |
| cellularComponent |
SMN complex
ⓘ
cytoplasmic ribonucleoprotein granules ⓘ nucleoplasm ⓘ |
| conservedIn | vertebrates ⓘ |
| encodedBy | DDX20 gene ⓘ |
| foundInTissue |
neuronal tissue
ⓘ
ubiquitously expressed tissues ⓘ |
| hasAlternativeName |
DDX20
ⓘ
DEAD-box helicase 20 ⓘ GEM-associated protein 3 ⓘ
linked to:
Gemin3
|
| hasDomain | DEAD-box helicase domain ⓘ |
| hasEnzymeClass | helicase ⓘ |
| hasLength | approximately 824 amino acids ⓘ |
| hasMolecularFunction |
ATP binding
ⓘ
ATP-dependent RNA helicase activity ⓘ RNA binding ⓘ |
| hasMotif | DEAD motif (Asp-Glu-Ala-Asp) ⓘ |
| interactsWith |
Gemin2
ⓘ
Gemin4 ⓘ SMN1 protein ⓘ
linked to:
survival motor neuron protein
spliceosomal snRNP proteins ⓘ |
| involvedIn |
RNA metabolism
ⓘ
U snRNA processing ⓘ pre-mRNA splicing ⓘ small nuclear ribonucleoprotein (snRNP) biogenesis ⓘ snRNP assembly ⓘ spliceosomal snRNP maturation ⓘ |
| locatedIn |
Gems (Gemini of Cajal bodies)
ⓘ
linked to:
gems (Gemini of Cajal bodies)
cytoplasm ⓘ nucleus ⓘ |
| organism | Homo sapiens ⓘ |
| partOf | SMN complex ⓘ |
| regulates |
snRNP assembly dynamics
ⓘ
snRNP stability ⓘ |
| requiresCofactor | ATP ⓘ |
| subcellularLocalization |
Cajal bodies-associated structures
ⓘ
nuclear gems ⓘ |
| taxon |
Eukaryota
ⓘ
linked to:
Eukarya
|
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Gemin3 Description of subject: Gemin3 is an RNA helicase and core component of the SMN complex that plays a crucial role in the assembly and metabolism of small nuclear ribonucleoproteins (snRNPs) involved in pre-mRNA splicing.
Referenced by (8)
Full triples — surface form annotated when it differs from this entity's canonical label.