Gemin8
E561089
Gemin8 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins (snRNPs) essential for pre-mRNA splicing.
All labels observed (2)
How this entity was disambiguated
This entity first appeared as the object of triple T6004694 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Gemin8 Context triple: [Survival motor neuron protein, formsComplexWith, Gemin8]
-
A.
Cygnus spacecraft
The Cygnus spacecraft is an uncrewed commercial cargo vehicle developed by Northrop Grumman to deliver supplies and scientific equipment to the International Space Station.
-
B.
Ares Express
Ares Express is a science fiction novel by Ian McDonald set on a far-future, terraformed Mars, blending adventure, surreal imagery, and rich world-building.
-
C.
Orion spacecraft
The Orion spacecraft is NASA’s next-generation crewed space vehicle designed to carry astronauts beyond low Earth orbit on deep-space missions, including journeys to the Moon and eventually Mars.
-
D.
Gemini 2
Gemini 2 was an uncrewed test flight in NASA's Gemini program that validated the spacecraft’s heat shield and reentry systems in preparation for later crewed missions.
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E.
Gemini 9A
Gemini 9A was a 1966 NASA crewed Gemini mission that tested rendezvous and docking procedures and conducted spacewalk experiments in preparation for the Apollo lunar program.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Gemin8 Target entity description: Gemin8 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins (snRNPs) essential for pre-mRNA splicing.
-
A.
Cygnus spacecraft
The Cygnus spacecraft is an uncrewed commercial cargo vehicle developed by Northrop Grumman to deliver supplies and scientific equipment to the International Space Station.
-
B.
Ares Express
Ares Express is a science fiction novel by Ian McDonald set on a far-future, terraformed Mars, blending adventure, surreal imagery, and rich world-building.
-
C.
Orion spacecraft
The Orion spacecraft is NASA’s next-generation crewed space vehicle designed to carry astronauts beyond low Earth orbit on deep-space missions, including journeys to the Moon and eventually Mars.
-
D.
Gemini 2
Gemini 2 was an uncrewed test flight in NASA's Gemini program that validated the spacecraft’s heat shield and reentry systems in preparation for later crewed missions.
-
E.
Gemini 9A
Gemini 9A was a 1966 NASA crewed Gemini mission that tested rendezvous and docking procedures and conducted spacewalk experiments in preparation for the Apollo lunar program.
- F. None of above. chosen
Statements (25)
| Predicate | Object |
|---|---|
| instanceOf |
SMN complex component
ⓘ
protein ⓘ |
| associatedWith |
SMN complex
ⓘ
survival motor neuron (SMN) protein ⓘ |
| associatedWithComplex |
Gemin6–Gemin7–Gemin8 subcomplex
ⓘ
linked to:
Gemin6
|
| associatedWithDisease | spinal muscular atrophy (via SMN complex dysfunction) ⓘ |
| associatedWithProcess |
RNA processing
ⓘ
spliceosomal snRNP biogenesis ⓘ |
| binds |
Gemin6
ⓘ
Gemin7 ⓘ SMN protein ⓘ
linked to:
survival motor neuron protein
|
| cellularComponent |
Cajal bodies
ⓘ
nuclear gem (Gemini of coiled bodies) ⓘ |
| fullName | gem-associated protein 8 ⓘ |
| geneName | GEMIN8 ⓘ |
| involvedIn |
assembly of small nuclear ribonucleoproteins
ⓘ
maturation of small nuclear ribonucleoproteins ⓘ pre-mRNA splicing ⓘ |
| locatedIn |
cytoplasm
ⓘ
nucleus ⓘ |
| molecularFunction |
RNA-binding complex assembly factor
ⓘ
protein binding ⓘ |
| organism | Homo sapiens ⓘ |
| partOf | SMN complex ⓘ |
| requiredFor | efficient snRNP assembly ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Gemin8 Description of subject: Gemin8 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins (snRNPs) essential for pre-mRNA splicing.
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject linked to:
survival motor neuron protein
linked to: Gemin8
subject linked to:
survival motor neuron protein