E2F transcription factor 3

URI: https://gptkb.org/entity/E2F_transcription_factor_3
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:transcription_factor
gptkb:protein
gptkbp:alternativeSplicing gptkb:E2F3a
gptkb:E2F3b
gptkbp:associatedWith gptkb:cancer
gptkbp:encodedBy gptkb:E2F3_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000112242
1871
gptkbp:expressedIn various tissues
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function regulation of cell cycle
transcriptional activation
transcriptional repression
gptkbp:gene gptkb:E2F3
gptkbp:has_molecular_function DNA binding
transcription factor activity
gptkbp:HGNC_ID gptkb:HGNC:3115
gptkbp:interactsWith gptkb:retinoblastoma_protein
gptkbp:involves p53 signaling pathway
cell cycle pathway
gptkbp:locatedOnChromosome 6p22
gptkbp:OMIM 600425
gptkbp:proteinFamily gptkb:E2F_family
gptkbp:regulates apoptosis
cell proliferation
cell cycle progression
DNA replication
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:UniProtID gptkb:O00716
gptkbp:bfsParent gptkb:E2F3
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label E2F transcription factor 3