Statements (18)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:catalyzes |
trimethylation of histone H3 at lysine 27 (H3K27me3)
|
gptkbp:component |
gptkb:Polycomb_Repressive_Complex_2_(PRC2)
|
gptkbp:discoveredIn |
Drosophila genetics studies
|
gptkbp:foundIn |
gptkb:Drosophila_melanogaster
|
gptkbp:function |
histone methyltransferase
|
gptkbp:gene |
gptkb:Enhancer_of_zeste_(E(z))_gene
|
https://www.w3.org/2000/01/rdf-schema#label |
E(z) protein
|
gptkbp:interactsWith |
gptkb:Esc_protein
gptkb:Nurf55_protein gptkb:Su(z)12_protein |
gptkbp:memberOf |
gptkb:Polycomb-group_proteins
|
gptkbp:mutationAssociatedWith |
homeotic transformations
|
gptkbp:orthologIn |
gptkb:EZH2_(in_humans)
|
gptkbp:role |
epigenetic gene silencing
developmental regulation |
gptkbp:bfsParent |
gptkb:Drosophila_E(z)
|
gptkbp:bfsLayer |
7
|