Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:endogenous_opioid_peptide
peptide |
| gptkbp:associatedWith |
gptkb:depression
addiction chronic pain stress-related disorders |
| gptkbp:binds |
gptkb:delta-opioid_receptor
gptkb:kappa-opioid_receptor gptkb:mu-opioid_receptor |
| gptkbp:discoveredBy |
gptkb:Avram_Goldstein
|
| gptkbp:effect |
can affect learning and memory
can inhibit neurotransmitter release can produce analgesia can produce dysphoria |
| gptkbp:encodedBy |
PDYN gene
|
| gptkbp:firstDescribed |
1979
|
| gptkbp:foundIn |
gptkb:pituitary_gland
gptkb:spinal_cord central nervous system hypothalamus |
| gptkbp:function |
modulation of pain
regulation of stress response control of appetite modulation of addiction regulation of emotion |
| https://www.w3.org/2000/01/rdf-schema#label |
Dynorphins
|
| gptkbp:majorForms |
dynorphin A
dynorphin B neo-endorphin |
| gptkbp:precursorProtein |
gptkb:prodynorphin
|
| gptkbp:relatedTo |
gptkb:enkephalins
endorphins |
| gptkbp:bfsParent |
gptkb:Endorphins
|
| gptkbp:bfsLayer |
7
|