Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:MKP-3
gptkb:PYST1 |
| gptkbp:biologicalProcess |
phosphatase activity
negative regulation of MAPK cascade |
| gptkbp:cellularComponent |
gptkb:cytoplasm
|
| gptkbp:encodes |
gptkb:Dual_specificity_protein_phosphatase_6
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000139318
1848 |
| gptkbp:expressedIn |
expressed in brain
expressed in heart expressed in pancreas |
| gptkbp:fullName |
dual specificity phosphatase 6
|
| gptkbp:function |
regulates cellular proliferation and differentiation
inactivates MAP kinases |
| gptkbp:HGNC_ID |
3071
|
| https://www.w3.org/2000/01/rdf-schema#label |
Dusp6
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12
|
| gptkbp:mutationAssociatedWith |
gptkb:Noonan_syndrome
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Dusp6 (mouse)
|
| gptkbp:pathway |
gptkb:MAPK_signaling_pathway
|
| gptkbp:proteinFamily |
dual specificity protein phosphatase
|
| gptkbp:regulates |
gptkb:ERK1
gptkb:ERK2 |
| gptkbp:UniProtID |
gptkb:Q16828
|
| gptkbp:bfsParent |
gptkb:DUSP6
|
| gptkbp:bfsLayer |
7
|