Dual Specificity Phosphatase
GPTKB entity
Statements (40)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:DUSP
|
| gptkbp:contains |
gptkb:DUSP1
gptkb:DUSP10 gptkb:DUSP11 gptkb:DUSP12 gptkb:DUSP13 gptkb:DUSP14 gptkb:DUSP16 gptkb:DUSP18 gptkb:DUSP19 gptkb:DUSP2 gptkb:DUSP21 gptkb:DUSP22 gptkb:DUSP23 gptkb:DUSP3 gptkb:DUSP4 gptkb:DUSP5 gptkb:DUSP6 gptkb:DUSP7 gptkb:DUSP8 gptkb:DUSP9 |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
DSP domain
|
| gptkbp:enzymeCommissionNumber |
gptkb:EC_3.1.3.16
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
dephosphorylation of phosphoserine/threonine and phosphotyrosine residues
|
| gptkbp:GO_term |
GO:0016791
|
| gptkbp:hasActivity |
phosphatase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
Dual Specificity Phosphatase
|
| gptkbp:inhibitedBy |
oxidative stress
|
| gptkbp:regulates |
MAP kinase signaling pathways
|
| gptkbp:relatedTo |
gptkb:cancer
apoptosis cell differentiation cell proliferation immune response cellular signaling |
| gptkbp:bfsParent |
gptkb:DUSP
|
| gptkbp:bfsLayer |
6
|