Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Dickkopf-related_protein_1
gptkb:Dkk-1 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:bone multiple myeloma |
| gptkbp:discoveredBy |
1998
|
| gptkbp:expressedIn |
gptkb:placenta
tumor cells bone tissue |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
Wnt signaling pathway inhibitor
regulation of embryonic development regulation of bone formation |
| gptkbp:gene |
gptkb:DKK1
|
| https://www.w3.org/2000/01/rdf-schema#label |
Dickkopf-1
|
| gptkbp:inhibitedBy |
gptkb:LRP5/6
gptkb:Wnt/β-catenin_signaling |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10q11.2
|
| gptkbp:molecularWeight |
27 kDa
|
| gptkbp:orthologInMouse |
gptkb:Dkk1
|
| gptkbp:PDB |
gptkb:2JTK
|
| gptkbp:secretes |
yes
|
| gptkbp:UniProtID |
O94907
|
| gptkbp:bfsParent |
gptkb:DKK1
|
| gptkbp:bfsLayer |
7
|