Dual specificity protein phosphatase 8

URI: https://gptkb.org/entity/Dual_specificity_protein_phosphatase_8
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:DUSP8
MKP-8
hVH5
gptkbp:biologicalProcess cellular response to stress
negative regulation of MAPK cascade
protein tyrosine/serine/threonine phosphatase activity
gptkbp:encodedBy DUSP8 gene
gptkbp:Entrez_Gene_ID GC11M002425
gptkbp:enzymeCommissionNumber 3.1.3.16
gptkbp:expressedIn gptkb:skeletal_muscle
gptkb:kidney
brain
heart
pancreas
gptkbp:family dual specificity protein phosphatase family
gptkbp:function dephosphorylation of phosphoserine/threonine and phosphotyrosine residues
gptkbp:HGNC_ID gptkb:HGNC:3072
https://www.w3.org/2000/01/rdf-schema#label Dual specificity protein phosphatase 8
gptkbp:locatedOnChromosome gptkb:11p15.5
chromosome 11
gptkbp:location gptkb:nucleus
gptkb:cytoplasm
gptkbp:OMIM 603115
gptkbp:organism gptkb:Homo_sapiens
gptkbp:RefSeq NM_004420
gptkbp:regulates mitogen-activated protein kinase (MAPK) pathways
gptkbp:UniProtID gptkb:Q13202
gptkbp:bfsParent gptkb:DUSP8
gptkbp:bfsLayer 7