|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:dopamine_receptor_D3
gptkb:dopamine_D3_receptor
D3DR
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
schizophrenia
drug addiction
|
|
gptkbp:chromosomeArm
|
3q13.31
|
|
gptkbp:discoveredBy
|
Sokoloff et al.
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodes
|
Dopamine D3 receptor
|
|
gptkbp:enemyOf
|
gptkb:haloperidol
pramipexole
7-OH-DPAT
eticlopride
raclopride
|
|
gptkbp:Entrez_Gene_ID
|
1814
ENSG00000151577
|
|
gptkbp:expressedIn
|
gptkb:nucleus_accumbens
brain
limbic system
islands of Calleja
|
|
gptkbp:fullName
|
Dopamine receptor D3
|
|
gptkbp:function
|
G-protein coupled receptor activity
dopamine receptor activity
neurotransmitter receptor activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3025
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DRD3
|
|
gptkbp:involvedIn
|
motor control
behavioral responses
reward pathway
dopaminergic synaptic transmission
|
|
gptkbp:length
|
400
|
|
gptkbp:ligand
|
dopamine
|
|
gptkbp:locatedOnChromosome
|
3
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:OMIM
|
601324
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Drd3
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:RefSeq
|
NM_000796
|
|
gptkbp:regulates
|
gptkb:cAMP_signaling_pathway
adenylate cyclase activity
|
|
gptkbp:target
|
antipsychotic drugs
antiparkinsonian drugs
|
|
gptkbp:transmembraneDomains
|
7
|
|
gptkbp:UniProtID
|
gptkb:P35462
|
|
gptkbp:bfsParent
|
gptkb:dopamine_receptor_D3
gptkb:Dopamine_D3_Receptor
|
|
gptkbp:bfsLayer
|
7
|