Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
TRDMT1
tRNA aspartic acid methyltransferase 1 |
| gptkbp:associatedWith |
stress response
cellular differentiation |
| gptkbp:biologicalProcess |
S-adenosyl-L-methionine-dependent methyltransferase activity
RNA modification epigenetic gene regulation tRNA methylation tRNA methyltransferase activity |
| gptkbp:cofactor |
gptkb:S-adenosyl-L-methionine
|
| gptkbp:conservedIn |
insects
mammals eukaryotes |
| gptkbp:discoveredBy |
Okano et al.
|
| gptkbp:Entrez_Gene_ID |
1787
ENSG00000107984 |
| gptkbp:enzymeCommissionNumber |
2.1.1.37
|
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:family |
DNA methyltransferase family
|
| gptkbp:fullName |
DNA (cytosine-5)-methyltransferase 2
|
| gptkbp:function |
has weak DNA methyltransferase activity
methylates cytosine-38 in tRNA(Asp) anticodon loop |
| gptkbp:gene |
TRDMT1
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
2976
|
| https://www.w3.org/2000/01/rdf-schema#label |
DNMT2
|
| gptkbp:interactsWith |
gptkb:tRNA(Asp)
other tRNAs |
| gptkbp:length |
391
|
| gptkbp:locatedOnChromosome |
10
|
| gptkbp:location |
10p13
|
| gptkbp:molecularWeight |
44 kDa
|
| gptkbp:OMIM |
606581
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:ortholog_in_Drosophila |
Mt2
|
| gptkbp:orthologInMouse |
Dnmt2
|
| gptkbp:PDB |
2Q0O
|
| gptkbp:RefSeq |
NM_004412
|
| gptkbp:regulates |
expression regulated by cellular stress
expression regulated during development |
| gptkbp:relatedTo |
DNA methylation
epigenetic regulation RNA methylation |
| gptkbp:structure |
contains methyltransferase domain
|
| gptkbp:subcellularLocation |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:UniProtID |
Q9Y6K1
|
| gptkbp:bfsParent |
gptkb:DNA_methyltransferase
|
| gptkbp:bfsLayer |
7
|