DNA mismatch repair protein MLH1
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
MutL homolog 1
hMLH1 |
| gptkbp:associatedWith |
gptkb:hereditary_nonpolyposis_colorectal_cancer
|
| gptkbp:discoveredBy |
gptkb:Richard_Kolodner
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
gptkb:MLH1_gene
|
| gptkbp:Entrez_Gene_ID |
4292
ENSG00000076242 |
| gptkbp:formsComplexWith |
gptkb:PMS2
gptkb:MLH3 PMS1 |
| gptkbp:function |
DNA mismatch repair
|
| gptkbp:interactsWith |
gptkb:MSH2
gptkb:MSH6 gptkb:PCNA gptkb:EXO1 |
| gptkbp:length |
756 amino acids
|
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
3p22.2
|
| gptkbp:molecularWeight |
85 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:Lynch_syndrome
microsatellite instability |
| gptkbp:OMIM |
120436
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
4P7A
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:RefSeq |
NP_000240.1
|
| gptkbp:UniProtID |
P40692
|
| gptkbp:bfsParent |
gptkb:MLH1
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
DNA mismatch repair protein MLH1
|