Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:hereditary_nonpolyposis_colorectal_cancer
|
| gptkbp:encodes |
DNA mismatch repair protein MLH3
|
| gptkbp:Entrez_Gene_ID |
27030
ENSG00000119684 |
| gptkbp:expressedIn |
gptkb:testis
|
| gptkbp:fullName |
MutL homolog 3
|
| gptkbp:function |
DNA mismatch repair
ATP binding meiotic recombination endonuclease activity |
| gptkbp:GOProcess |
mismatch repair
meiotic crossing over |
| gptkbp:HGNC_ID |
HGNC:7128
|
| https://www.w3.org/2000/01/rdf-schema#label |
MLH3
|
| gptkbp:interactsWith |
gptkb:MLH1
MSH4 MSH5 |
| gptkbp:length |
1,454 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_14
|
| gptkbp:location |
14q24.3
|
| gptkbp:molecularWeight |
164 kDa
|
| gptkbp:mutationAssociatedWith |
increased cancer risk
genomic instability |
| gptkbp:OMIM |
604395
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
yeast MLH3
|
| gptkbp:proteinFamily |
MutL family
|
| gptkbp:UniProtID |
Q9UHC1
|
| gptkbp:bfsParent |
gptkb:MLH1
|
| gptkbp:bfsLayer |
6
|