Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alias |
Delta-like 1 homolog (Drosophila)
|
| gptkbp:alternativeName |
FA1
Delta-like homolog 1 Fetal antigen 1 PREF1 |
| gptkbp:associatedWith |
gptkb:cancer
obesity growth disorders precocious puberty |
| gptkbp:discoveredBy |
Laborda J et al.
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodes |
Delta-like 1 homolog protein
|
| gptkbp:Entrez_Gene_ID |
8788
ENSG00000185559 |
| gptkbp:expressedIn |
adipose tissue
neuroendocrine tissues fetal liver |
| gptkbp:fullName |
Delta-like 1 homolog
|
| gptkbp:function |
regulation of cell differentiation
regulation of neurogenesis inhibition of adipogenesis |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
2896
|
| https://www.w3.org/2000/01/rdf-schema#label |
DLK1
|
| gptkbp:imprint |
paternally expressed
|
| gptkbp:imprintedGene |
true
|
| gptkbp:imprintingCluster |
DLK1-DIO3 region
|
| gptkbp:locatedOnChromosome |
chromosome 14q32
|
| gptkbp:location |
gptkb:cell_membrane
extracellular space |
| gptkbp:memberOf |
EGF-like family
|
| gptkbp:molecularWeight |
~50 kDa
|
| gptkbp:mutationAssociatedWith |
can cause central precocious puberty
can cause familial obesity |
| gptkbp:neighboringGene |
DIO3
MEG3 RTL1 |
| gptkbp:OMIM |
176290
|
| gptkbp:orthologInMouse |
Dlk1
|
| gptkbp:pathway |
gptkb:Notch_signaling_pathway
adipogenesis pathway |
| gptkbp:product |
contains EGF-like repeats
|
| gptkbp:proteinFamily |
Notch ligand family
|
| gptkbp:regulates |
stem cell maintenance
preadipocyte differentiation |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:transmembraneDomains |
true
|
| gptkbp:UniProtID |
P80370
|
| gptkbp:bfsParent |
gptkb:chromosome_14
|
| gptkbp:bfsLayer |
7
|