|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
Delta-like 1 homolog (Drosophila)
|
|
gptkbp:alternativeName
|
FA1
Delta-like homolog 1
Fetal antigen 1
PREF1
|
|
gptkbp:associatedWith
|
gptkb:cancer
obesity
growth disorders
precocious puberty
|
|
gptkbp:discoveredBy
|
Laborda J et al.
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodes
|
Delta-like 1 homolog protein
|
|
gptkbp:Entrez_Gene_ID
|
8788
ENSG00000185559
|
|
gptkbp:expressedIn
|
gptkb:adipose_tissue
neuroendocrine tissues
fetal liver
|
|
gptkbp:fullName
|
Delta-like 1 homolog
|
|
gptkbp:function
|
regulation of cell differentiation
regulation of neurogenesis
inhibition of adipogenesis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
2896
|
|
gptkbp:imprint
|
paternally expressed
|
|
gptkbp:imprintedGene
|
true
|
|
gptkbp:imprintingCluster
|
DLK1-DIO3 region
|
|
gptkbp:locatedOnChromosome
|
chromosome 14q32
|
|
gptkbp:location
|
gptkb:cell_membrane
extracellular space
|
|
gptkbp:memberOf
|
EGF-like family
|
|
gptkbp:molecularWeight
|
~50 kDa
|
|
gptkbp:mutationAssociatedWith
|
can cause central precocious puberty
can cause familial obesity
|
|
gptkbp:neighboringGene
|
DIO3
MEG3
RTL1
|
|
gptkbp:OMIM
|
176290
|
|
gptkbp:orthologInMouse
|
Dlk1
|
|
gptkbp:pathway
|
gptkb:Notch_signaling_pathway
adipogenesis pathway
|
|
gptkbp:product
|
contains EGF-like repeats
|
|
gptkbp:proteinFamily
|
Notch ligand family
|
|
gptkbp:regulates
|
stem cell maintenance
preadipocyte differentiation
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:UniProtID
|
P80370
|
|
gptkbp:bfsParent
|
gptkb:chromosome_14
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DLK1
|