|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
CD209
|
|
gptkbp:binds
|
gptkb:HIV-1_gp120
gptkb:ICAM-2
gptkb:ICAM-3
Ebola virus glycoprotein
Dengue virus envelope protein
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
Yvette van Kooyk
|
|
gptkbp:discoveredIn
|
2000
|
|
gptkbp:encodedBy
|
CD209 gene
|
|
gptkbp:Entrez_Gene_ID
|
30835
ENSG00000116031
|
|
gptkbp:expressedIn
|
dendritic cells
macrophages
|
|
gptkbp:family
|
gptkb:C-type_lectin_family
|
|
gptkbp:form
|
tetramer
|
|
gptkbp:foundIn
|
gptkb:human
|
|
gptkbp:function
|
cell adhesion
immune response modulation
pathogen recognition
|
|
gptkbp:glycosylation
|
N-linked
|
|
gptkbp:HGNC_ID
|
1641
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DC-SIGN
|
|
gptkbp:interactsWith
|
gptkb:Cytomegalovirus
gptkb:Mycobacterium_tuberculosis
gptkb:Leishmania
gptkb:Hepatitis_C_virus
|
|
gptkbp:ligand
|
fucose-containing glycans
high-mannose oligosaccharides
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:OMIM
|
604672
|
|
gptkbp:orthologIn
|
mouse (SIGNR1)
|
|
gptkbp:pathway
|
innate immune response
antigen processing and presentation
|
|
gptkbp:postTranslationalModification
|
glycosylation
|
|
gptkbp:recipient
|
pattern recognition receptor
|
|
gptkbp:role
|
antigen presentation
HIV transmission
immune evasion by pathogens
|
|
gptkbp:significance
|
HIV infection
immune disorders
viral pathogenesis
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
C-type lectin domain
|
|
gptkbp:subcellularLocation
|
cell surface
|
|
gptkbp:UniProtID
|
Q9NNX6
|
|
gptkbp:bfsParent
|
gptkb:Dengue_virus
|
|
gptkbp:bfsLayer
|
7
|