Cytokine-Induced Killer cell

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:immune_response
gptkbp:abbreviation	gptkb:CIK_cell
gptkbp:abilities	tumor cells virus-infected cells
gptkbp:advantage	low risk of graft-versus-host disease broad tumor cell recognition
gptkbp:clinicalTrialPhase	solid tumors hematological malignancies
gptkbp:derivedFrom	peripheral blood mononuclear cells
gptkbp:discoveredBy	gptkb:Zhinan_Yin
gptkbp:discoveredIn	1991
gptkbp:expansion	gptkb:anti-CD3_antibody cytokines
gptkbp:expressedIn	gptkb:CD56 gptkb:NKG2D gptkb:CD3 gptkb:CD8
gptkbp:function	gptkb:immunotherapy cytotoxicity against tumor cells
gptkbp:MHC_restriction	non-MHC restricted
gptkbp:origin	gptkb:human mouse (experimental)
gptkbp:proliferationStimulatedBy	gptkb:anti-CD3_antibody gptkb:interferon-gamma gptkb:interleukin-2 gptkb:interleukin-1
gptkbp:relatedTo	T lymphocyte natural killer cell
gptkbp:usedIn	gptkb:cancer adoptive cell therapy
gptkbp:bfsParent	gptkb:CIK_cell
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Cytokine-Induced Killer cell