Cytokine-Induced Killer cell

URI: https://gptkb.org/entity/Cytokine-Induced_Killer_cell
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf immune response
gptkbp:abbreviation gptkb:CIK_cell
gptkbp:abilities tumor cells
virus-infected cells
gptkbp:advantage low risk of graft-versus-host disease
broad tumor cell recognition
gptkbp:clinicalTrialPhase solid tumors
hematological malignancies
gptkbp:derivedFrom peripheral blood mononuclear cells
gptkbp:discoveredBy gptkb:Zhinan_Yin
gptkbp:discoveredIn 1991
gptkbp:expansion gptkb:anti-CD3_antibody
cytokines
gptkbp:expressedIn gptkb:CD56
gptkb:NKG2D
gptkb:CD3
gptkb:CD8
gptkbp:function immunotherapy
cytotoxicity against tumor cells
https://www.w3.org/2000/01/rdf-schema#label Cytokine-Induced Killer cell
gptkbp:MHC_restriction non-MHC restricted
gptkbp:origin gptkb:human
mouse (experimental)
gptkbp:proliferationStimulatedBy gptkb:anti-CD3_antibody
gptkb:interferon-gamma
gptkb:interleukin-2
gptkb:interleukin-1
gptkbp:relatedTo T lymphocyte
natural killer cell
gptkbp:usedIn gptkb:cancer
adoptive cell therapy
gptkbp:bfsParent gptkb:CIK_cell
gptkbp:bfsLayer 7