Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alias |
CCNE1 protein
G1/S-specific cyclin-E1 |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:degradedBy |
gptkb:ubiquitin-proteasome_pathway
|
| gptkbp:encodedBy |
gptkb:CCNE1_gene
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:G1/S_transition_of_cell_cycle
regulation of cell cycle |
| https://www.w3.org/2000/01/rdf-schema#label |
Cyclin E1 protein
|
| gptkbp:interactsWith |
CDK2 protein
|
| gptkbp:involvedIn |
cell proliferation
DNA replication |
| gptkbp:locatedOnChromosome |
19q12
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:molecularWeight |
47 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:overexpressedIn |
gptkb:cancer
|
| gptkbp:phosphorylates |
Serine 384
|
| gptkbp:regulates |
transcriptional control
proteolytic degradation CDK2 activity |
| gptkbp:structure |
contains cyclin box domain
|
| gptkbp:UniProtID |
P24864
|
| gptkbp:bfsParent |
gptkb:CCNE1
|
| gptkbp:bfsLayer |
7
|