|
gptkbp:instanceOf
|
gptkb:drug
gptkb:Corticosteroid
Steroid hormone
|
|
gptkbp:administeredBy
|
gptkb:Injection
Oral route
|
|
gptkbp:ATCCode
|
H02AB10
|
|
gptkbp:brand
|
gptkb:Cortone
|
|
gptkbp:CASNumber
|
53-06-5
|
|
gptkbp:category
|
Hormones
Corticosteroids
Immunosuppressants
Anti-inflammatory agents
|
|
gptkbp:chemicalFormula
|
C21H28O5
|
|
gptkbp:convertedTo
|
gptkb:Cortisol
|
|
gptkbp:discoveredBy
|
gptkb:Edward_Calvin_Kendall
|
|
gptkbp:discoveredIn
|
1935
|
|
gptkbp:excretion
|
gptkb:Kidneys
|
|
gptkbp:foundIn
|
gptkb:Humans
gptkb:Mammals
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cortisone
|
|
gptkbp:IUPACName
|
gptkb:17-hydroxy-11-dehydrocorticosterone
|
|
gptkbp:legalStatus
|
Prescription only
|
|
gptkbp:meltingPoint
|
220°C
|
|
gptkbp:MeSH_ID
|
D003418
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:molecularWeight
|
360.44 g/mol
|
|
gptkbp:predecessor
|
gptkb:Cortisol
|
|
gptkbp:producedBy
|
gptkb:Adrenal_cortex
|
|
gptkbp:PubChem_CID
|
222786
CHEBI:16962
|
|
gptkbp:relatedTo
|
gptkb:Corticosterone
gptkb:Hydrocortisone
gptkb:Prednisolone
gptkb:Prednisone
|
|
gptkbp:routeOfAdministration
|
gptkb:Oral
Intramuscular
Intravenous
|
|
gptkbp:sideEffect
|
Weight gain
Hypertension
Hyperglycemia
Osteoporosis
Mood changes
|
|
gptkbp:UNII
|
7S5I7G3JQL
|
|
gptkbp:usedFor
|
Immunosuppression
Anti-inflammatory therapy
Treatment of adrenal insufficiency
|
|
gptkbp:bfsParent
|
gptkb:Upjohn
|
|
gptkbp:bfsLayer
|
5
|