Cortisol

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf hormone
gptkbp:affects protein metabolism
blood pressure
immune system
fat metabolism
circadian rhythm
memory formation
blood sugar levels
gptkbp:alsoKnownAs hydrocortisone
gptkbp:awarded Nobel Prize in Physiology or Medicine 1950
gptkbp:category gptkb:Corticosteroid
endocrinology
hormone
stress hormone
gptkbp:chemicalFormula C21H30O5
gptkbp:decreasedIn sleep
relaxation
gptkbp:deficiencyCauses Addison's disease
gptkbp:discoveredBy gptkb:Edward_Calvin_Kendall
gptkb:Tadeus_Reichstein
gptkb:Philip_S._Hench
gptkbp:discoveredIn 1936
gptkbp:excessLeadsTo gptkb:Cushing's_syndrome
gptkbp:foundIn urine
blood plasma
saliva
gptkbp:halfLife 60-90 minutes
gptkbp:hasBiologicalActivity gptkb:Corticosteroid
https://www.w3.org/2000/01/rdf-schema#label Cortisol
gptkbp:improves stress
exercise
gptkbp:meltingPoint 220 °C
gptkbp:molecularWeight 362.46 g/mol
gptkbp:predecessor gptkb:androgens
gptkb:cortisone
gptkb:aldosterone
gptkbp:producedBy adrenal cortex
gptkbp:regulates gptkb:adrenocorticotropic_hormone
metabolism
immune response
stress response
gptkbp:solubility slightly soluble in water
soluble in alcohol
gptkbp:usedAs gptkb:drug
gptkbp:usedFor allergic reactions
adrenal insufficiency
inflammatory conditions
gptkbp:bfsParent gptkb:Adrenal_Gland
gptkb:Cholesterol
gptkb:Cortisone
gptkb:Corticosteroid
gptkbp:bfsLayer 6