Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Corticosteroid
|
| gptkbp:approvedBy |
1955
|
| gptkbp:ATCCode |
H02AB06
|
| gptkbp:brand |
Millipred
Orapred Pediapred Prelone |
| gptkbp:CASNumber |
50-24-8
|
| gptkbp:contraindication |
systemic fungal infections
hypersensitivity to prednisolone |
| gptkbp:discoveredBy |
gptkb:Arthur_Nobile
|
| gptkbp:eliminationHalfLife |
2-4 hours
|
| gptkbp:hasMolecularFormula |
C21H28O5
|
| https://www.w3.org/2000/01/rdf-schema#label |
Prednisolone
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
reduces inflammation
binds to glucocorticoid receptor modulates gene expression suppresses immune response |
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:relatedTo |
gptkb:prednisone
gptkb:methylprednisolone hydrocortisone |
| gptkbp:routeOfAdministration |
oral
topical intravenous ophthalmic |
| gptkbp:sideEffect |
gptkb:cataracts
gptkb:bone immunosuppression hypertension glaucoma mood changes weight gain insomnia hyperglycemia |
| gptkbp:usedFor |
gptkb:Crohn's_disease
asthma ulcerative colitis autoimmune diseases rheumatoid arthritis allergic reactions nephrotic syndrome adrenal insufficiency organ transplant rejection prevention inflammatory conditions dermatologic diseases multiple sclerosis exacerbations ophthalmic diseases |
| gptkbp:bfsParent |
gptkb:Cortisone
gptkb:Corticosteroid |
| gptkbp:bfsLayer |
6
|