|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:activeIngredient
|
gptkb:amoxicillin
gptkb:clavulanic_acid
|
|
gptkbp:administeredBy
|
animals
humans
|
|
gptkbp:alsoKnownAs
|
amoxicillin/clavulanic acid
|
|
gptkbp:approvalYear
|
1984
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J01CR02
|
|
gptkbp:brand
|
gptkb:Curam
gptkb:Synulox
gptkb:Augmentin
gptkb:Clavamox
|
|
gptkbp:category
|
gptkb:beta-lactam_antibiotics
penicillin antibiotics
beta-lactamase inhibitors
|
|
gptkbp:chemicalFormula
|
C16H19N3O5S (amoxicillin), C8H9NO5 (clavulanic acid)
|
|
gptkbp:combinationTherapy
|
true
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:developedBy
|
gptkb:Beecham
|
|
gptkbp:discoveredIn
|
1981
|
|
gptkbp:drugInteraction
|
gptkb:warfarin
gptkb:methotrexate
allopurinol
oral contraceptives
|
|
gptkbp:eliminationHalfLife
|
1 hour
|
|
gptkbp:excretion
|
renal
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Co-amoxiclav
|
|
gptkbp:indication
|
urinary tract infections
respiratory tract infections
dental infections
skin and soft tissue infections
bone and joint infections
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
inhibits beta-lactamase enzymes
|
|
gptkbp:overdoseSymptoms
|
renal dysfunction
gastrointestinal upset
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:prescribes
|
adults
children
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
rash
liver dysfunction
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Augmentin
gptkb:Zentiva
|
|
gptkbp:bfsLayer
|
7
|