|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
7
|
|
gptkbp:bfsParent
|
gptkb:Celebrex
|
|
gptkbp:activities
|
COX-2 inhibitor
|
|
gptkbp:approves
|
gptkb:1998
gptkb:FDA
|
|
gptkbp:brand
|
gptkb:Celebrex
|
|
gptkbp:class
|
gptkb:drug
|
|
gptkbp:clinical_trial
|
gptkb:ankylosing_spondylitis
Phase III
menstrual pain
chronic pain management
post-operative pain
acute gouty arthritis
|
|
gptkbp:composed_of
|
via cyclization of 4-(methylsulfonyl)aniline
|
|
gptkbp:contraindication
|
active gastrointestinal bleeding
severe heart disease
sulfa allergy
|
|
gptkbp:developed_by
|
gptkb:Pharmacia
|
|
gptkbp:dissolved
|
soluble in ethanol
slightly soluble in water
|
|
gptkbp:dosage_form
|
100-200 mg daily
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:formulation
|
oral tablet
oral capsule
oral suspension
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Celecoxib
|
|
gptkbp:indication
|
gptkb:rheumatoid_arthritis
osteoarthritis
acute pain
dysmenorrhea
|
|
gptkbp:ingredients
|
C17 H14 F3 N3 O2 S
|
|
gptkbp:interacts_with
|
gptkb:warfarin
aspirin
other NSAI Ds
|
|
gptkbp:invention
|
gptkb:2014
|
|
gptkbp:is_available_on
|
gptkb:beer
suspension
|
|
gptkbp:is_used_for
|
pain relief
arthritis treatment
inflammation reduction
|
|
gptkbp:lifespan
|
11 hours
|
|
gptkbp:manager
|
oral
|
|
gptkbp:marketed_as
|
gptkb:Pfizer
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:previous_name
|
gptkb:Celecoxib
|
|
gptkbp:safety_features
|
Category C (pregnancy)
|
|
gptkbp:side_effect
|
headache
nausea
diarrhea
liver damage
cardiovascular events
stomach pain
kidney problems
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:traded_on
|
gptkb:Celebrex
|
|
gptkbp:type_of
|
169590-42-5
|
|
gptkbp:weight
|
381.37 g/mol
|