Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
microscopy technique
|
| gptkbp:advantage |
no need for crystallization
studies large complexes |
| gptkbp:field |
biochemistry
molecular biology structural biology |
| gptkbp:fullName |
cryo-electron microscopy
|
| https://www.w3.org/2000/01/rdf-schema#label |
cryo-EM
|
| gptkbp:inventedBy |
1980s
|
| gptkbp:limitation |
low contrast
radiation damage |
| gptkbp:NobelPrizeYear |
gptkb:Jacques_Dubochet
gptkb:Joachim_Frank gptkb:Richard_Henderson 2017 |
| gptkbp:notableAdvancement |
single-particle analysis
|
| gptkbp:relatedTo |
X-ray crystallography
NMR spectroscopy |
| gptkbp:resolution |
near-atomic
|
| gptkbp:samplePreparation |
vitrification
|
| gptkbp:usedFor |
structural biology
protein structure determination virus structure analysis |
| gptkbp:uses |
gptkb:electron_microscope
cryogenic temperatures |
| gptkbp:bfsParent |
gptkb:U6_snRNA
gptkb:Cas13a gptkb:BioSAXS |
| gptkbp:bfsLayer |
7
|