Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:NOX2
gptkb:gp91phox gptkb:phagocyte_oxidase |
| gptkbp:associatedWith |
gptkb:chronic_granulomatous_disease
|
| gptkbp:discoveredBy |
1987
|
| gptkbp:encodes |
gptkb:NADPH_oxidase_2_(NOX2)
|
| gptkbp:Entrez_Gene_ID |
1536
ENSG00000165168 |
| gptkbp:expressedIn |
phagocytes
|
| gptkbp:fullName |
gptkb:cytochrome_b-245_beta_chain
|
| gptkbp:function |
catalyzes the reduction of oxygen to superoxide in phagocytes
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:2567
|
| https://www.w3.org/2000/01/rdf-schema#label |
CYBB
|
| gptkbp:inheritance |
X-linked
|
| gptkbp:locatedOnChromosome |
X
|
| gptkbp:location |
gptkb:Xp21.1
|
| gptkbp:mutationAssociatedWith |
impaired respiratory burst
|
| gptkbp:OMIM |
300481
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Cybb
|
| gptkbp:pathway |
innate immune response
reactive oxygen species generation |
| gptkbp:UniProtID |
P04839
|
| gptkbp:bfsParent |
gptkb:Kugaaruk_Airport
|
| gptkbp:bfsLayer |
6
|