Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
assembly at phagosomal membrane
|
| gptkbp:alsoKnownAs |
gptkb:NADPH_oxidase
|
| gptkbp:component |
gptkb:gp91phox
p22phox p40phox p67phox Rac GTPase p47phox |
| gptkbp:deficiencyCauses |
gptkb:chronic_granulomatous_disease
|
| gptkbp:discoveredBy |
Bernard Babior
|
| gptkbp:EC_number |
1.6.3.1
|
| gptkbp:function |
produces reactive oxygen species
generates superoxide |
| gptkbp:gene |
gptkb:CYBA
gptkb:NCF1 gptkb:NCF2 gptkb:NCF4 gptkb:CYBB |
| gptkbp:location |
phagocytes
|
| gptkbp:product |
gptkb:superoxide_anion
|
| gptkbp:roleInImmunity |
microbial killing
|
| gptkbp:substrate |
oxygen
NADPH |
| gptkbp:bfsParent |
gptkb:CYBB
|
| gptkbp:bfsLayer |
7
|
| http://www.w3.org/2000/01/rdf-schema#label |
phagocyte oxidase
|