|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
GATAD1
Mi-2 beta
Mi2B
|
|
gptkbp:associatedWith
|
gptkb:cancer
Sifrim-Hitz-Weiss syndrome
|
|
gptkbp:domain
|
helicase domain
PHD finger
chromodomain
|
|
gptkbp:encodedBy
|
CHD4 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000171316
1108
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
Chromodomain-helicase-DNA-binding protein 4
|
|
gptkbp:function
|
chromatin binding
transcriptional repression
chromatin remodeling
ATP-dependent DNA helicase activity
|
|
gptkbp:GOProcess
|
DNA repair
regulation of transcription
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CHD4
|
|
gptkbp:interactsWith
|
gptkb:MBD3
gptkb:HDAC1
gptkb:RBBP4
MTA1
|
|
gptkbp:involvedIn
|
cell differentiation
embryonic development
chromatin organization
|
|
gptkbp:length
|
1912 amino acids
|
|
gptkbp:locatedOnChromosome
|
12q24.31
|
|
gptkbp:memberOf
|
gptkb:NuRD_complex
|
|
gptkbp:molecularWeight
|
218 kDa
|
|
gptkbp:mutationAssociatedWith
|
intellectual disability
developmental delay
congenital anomalies
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInFruitFly
|
gptkb:Mi-2
|
|
gptkbp:orthologInMouse
|
Chd4
|
|
gptkbp:orthologInZebrafish
|
chd4a
|
|
gptkbp:PDB
|
6RYR
6RYU
|
|
gptkbp:regulates
|
gene expression
cell cycle
DNA damage response
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
Q14839
|
|
gptkbp:bfsParent
|
gptkb:CHD7
|
|
gptkbp:bfsLayer
|
7
|