|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
CHD-3
Mi-2-alpha
Mi2-alpha
|
|
gptkbp:associatedWith
|
neurodevelopmental disorders
|
|
gptkbp:biologicalProcess
|
cell differentiation
DNA repair
transcription regulation
chromatin remodeling
|
|
gptkbp:discoveredBy
|
Mi-2 autoantibody studies
|
|
gptkbp:domain
|
PHD-type zinc finger
helicase domain
chromodomain
|
|
gptkbp:encodedBy
|
CHD3 gene
|
|
gptkbp:Entrez_Gene_ID
|
1107
ENSG00000170004
|
|
gptkbp:expressedIn
|
gptkb:kidney
gptkb:testis
brain
liver
|
|
gptkbp:fullName
|
Chromodomain-helicase-DNA-binding protein 3
|
|
gptkbp:function
|
chromatin binding
chromatin remodeling
ATP-dependent DNA helicase activity
|
|
gptkbp:GOMolecularComponent
|
gptkb:nucleus
nucleosome remodeling and deacetylase complex
|
|
gptkbp:hasParalog
|
gptkb:CHD4
gptkb:CHD5
|
|
gptkbp:HGNC_ID
|
1911
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CHD3
|
|
gptkbp:interactsWith
|
gptkb:GATAD2A
gptkb:HDAC1
gptkb:RBBP4
MTA2
|
|
gptkbp:length
|
2000 amino acids
|
|
gptkbp:locatedIn
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
17p13.1
|
|
gptkbp:memberOf
|
Mi-2/NuRD complex
|
|
gptkbp:molecularWeight
|
227 kDa
|
|
gptkbp:mutationAssociatedWith
|
Snijders Blok-Campeau syndrome
|
|
gptkbp:OMIM
|
603277
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:phosphorylates
|
Serine 1502
Serine 1530
|
|
gptkbp:UniProtID
|
Q12873
|
|
gptkbp:bfsParent
|
gptkb:CHD7
|
|
gptkbp:bfsLayer
|
7
|