Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alias |
CDC18L
cell division cycle 6 homolog |
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:encodedBy |
CDC6 gene
|
| gptkbp:Entrez_Gene_ID |
990
ENSG00000094804 |
| gptkbp:expressedIn |
proliferating cells
|
| gptkbp:foundIn |
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens |
| gptkbp:function |
cell cycle regulation
DNA replication initiation |
| gptkbp:GO_term |
GO:0006270 (DNA replication initiation)
GO:0007049 (cell cycle) |
| https://www.w3.org/2000/01/rdf-schema#label |
CDC6
|
| gptkbp:interactsWith |
gptkb:CDK2
ORC complex |
| gptkbp:length |
560 amino acids
|
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
17q21.3
|
| gptkbp:molecularWeight |
65 kDa
|
| gptkbp:mutationAssociatedWith |
Meier-Gorlin syndrome
|
| gptkbp:orthologIn |
Cdc18 (Schizosaccharomyces pombe)
|
| gptkbp:PDB |
2V2U
|
| gptkbp:phosphorylates |
gptkb:CDK2
|
| gptkbp:regulates |
degraded by APC/C
regulated by E2F transcription factors |
| gptkbp:UniProtID |
Q99741
|
| gptkbp:bfsParent |
gptkb:R-HSA-5673003
|
| gptkbp:bfsLayer |
7
|