Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:ICAM-1
|
| gptkbp:binds |
gptkb:LFA-1
gptkb:Mac-1 |
| gptkbp:encodedBy |
gptkb:ICAM1_gene
|
| gptkbp:Entrez_Gene_ID |
3383
|
| gptkbp:expressedIn |
endothelial cells
inflammatory response immune cells |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
immune response
cell adhesion |
| gptkbp:hasRole |
T cell activation
antigen presentation |
| https://www.w3.org/2000/01/rdf-schema#label |
CD54
|
| gptkbp:involvedIn |
inflammation
leukocyte transmigration |
| gptkbp:locatedOnChromosome |
gptkb:19p13.2
|
| gptkbp:location |
cell surface
|
| gptkbp:molecularWeight |
~85-110 kDa
|
| gptkbp:OMIM |
147840
|
| gptkbp:structure |
gptkb:immunoglobulin_superfamily
|
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:UniProtID |
gptkb:P05362
|
| gptkbp:upregulatedBy |
inflammatory cytokines
|
| gptkbp:usedAs |
biomarker
|
| gptkbp:bfsParent |
gptkb:ICAM-1
gptkb:ICAM1 |
| gptkbp:bfsLayer |
7
|