Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CD4_glycoprotein
|
| gptkbp:antibodyTarget |
gptkb:Leu-3
gptkb:OKT4 |
| gptkbp:binds |
gptkb:MHC_class_II_molecules
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:CD4_gene
|
| gptkbp:Entrez_Gene_ID |
920
|
| gptkbp:expressedIn |
gptkb:regulatory_T_cells
gptkb:microglia thymocytes |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
coreceptor for T cell receptor
mediates immune response |
| gptkbp:HGNC_ID |
1678
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD4 receptor
|
| gptkbp:locatedOn |
dendritic cells
macrophages monocytes surface of T helper cells |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12_(human)
|
| gptkbp:molecularWeight |
~55 kDa
|
| gptkbp:OMIM |
186940
|
| gptkbp:PDB |
1WIP
|
| gptkbp:significance |
marker for T helper cells
used to monitor HIV/AIDS progression |
| gptkbp:structure |
single-chain transmembrane glycoprotein
|
| gptkbp:target |
gptkb:HIV
|
| gptkbp:UniProtID |
P01730
|
| gptkbp:usedBy |
HIV to enter cells
|
| gptkbp:bfsParent |
gptkb:gp120
|
| gptkbp:bfsLayer |
6
|