CD3e molecule, epsilon (CD3-TCR complex)

URI: https://gptkb.org/entity/CD3e_molecule,_epsilon_(CD3-TCR_complex)
GPTKB entity
Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:CD3_epsilon_chain
gptkb:T3E
gptkb:T-cell_surface_glycoprotein_CD3_epsilon_chain
gptkbp:associatedWith immunodeficiency
gptkbp:biologicalProcess gptkb:T_cell_receptor_signaling_pathway
adaptive immune response
gptkbp:cellularComponent integral component of membrane
gptkbp:component gptkb:T-cell_receptor-CD3_complex
gptkbp:encodedBy gptkb:CD3E_gene
gptkbp:Entrez_Gene_ID gptkb:CD3E
ENSG00000198851
gptkbp:expressedIn T lymphocytes
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function signal transduction
T-cell activation
gptkbp:gene gptkb:CD3E
gptkbp:HGNC_ID 1675
https://www.w3.org/2000/01/rdf-schema#label CD3e molecule, epsilon (CD3-TCR complex)
gptkbp:interactsWith gptkb:CD3G
gptkb:TCR_alpha_chain
gptkb:TCR_beta_chain
gptkb:CD3D
CD247 (CD3Z)
gptkbp:locatedIn chromosome 11
gptkbp:location gptkb:plasma_membrane
gptkbp:molecularWeight 20-25 kDa
gptkbp:mutationAssociatedWith gptkb:severe_combined_immunodeficiency_(SCID)
gptkbp:OMIM 186830
gptkbp:PDB 1XIW
gptkbp:postTranslationalModification phosphorylation
gptkbp:RefSeq gptkb:NM_000733
gptkbp:UniProtID P07766
gptkbp:bfsParent gptkb:CD3E
gptkbp:bfsLayer 7