|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CD30
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:anaplastic_large_cell_lymphoma
Hodgkin lymphoma
|
|
gptkbp:biologicalProcess
|
immune system process
tumor necrosis factor-activated receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
Stein et al.
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodes
|
CD30 protein
|
|
gptkbp:Entrez_Gene_ID
|
943
ENSG00000010610
|
|
gptkbp:expressedIn
|
gptkb:Reed-Sternberg_cells
activated T cells
|
|
gptkbp:fullName
|
Tumor necrosis factor receptor superfamily member 8
|
|
gptkbp:function
|
regulation of apoptosis
immune response modulation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
11921
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TNFRSF8
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p36
chromosome 1
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:OMIM
|
153243
|
|
gptkbp:orthologInMouse
|
Tnfrsf8
|
|
gptkbp:product
|
cell surface receptor
|
|
gptkbp:targetOfDrug
|
gptkb:brentuximab_vedotin
|
|
gptkbp:UniProtID
|
gptkb:P28908
|
|
gptkbp:bfsParent
|
gptkb:CD30
|
|
gptkbp:bfsLayer
|
7
|