|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:B7-H3
gptkb:B7_homolog_3
|
|
gptkbp:associatedWith
|
tumor progression
poor prognosis in cancer
|
|
gptkbp:cellSurfaceMarker
|
yes
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:encodedBy
|
CD276 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000103855
80381
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:function
|
immune checkpoint molecule
regulation of T cell-mediated immune response
|
|
gptkbp:glycosylation
|
yes
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:19158
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD276
|
|
gptkbp:interactsWith
|
gptkb:NK_cells
gptkb:T_cells
|
|
gptkbp:locatedOnChromosome
|
gptkb:15q24.1
|
|
gptkbp:memberOf
|
gptkb:B7_family
|
|
gptkbp:molecularWeight
|
~57 kDa
|
|
gptkbp:overexpressedIn
|
several cancers
|
|
gptkbp:potentialTherapeuticTargetFor
|
immunotherapy
|
|
gptkbp:regulates
|
immune response
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
type I transmembrane protein
|
|
gptkbp:UniProtID
|
gptkb:Q5ZPR3
|
|
gptkbp:bfsParent
|
gptkb:immunoglobulin_superfamily
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:bfsLayer
|
7
|