Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alias |
HP1-beta
Heterochromatin Protein 1 beta |
gptkbp:associatedWith |
gptkb:cancer
intellectual disability |
gptkbp:Entrez_Gene_ID |
10951
ENSG00000169045 |
gptkbp:fullName |
Chromobox protein homolog 1
|
gptkbp:function |
transcriptional repression
binds methylated histone H3 involved in heterochromatin formation |
gptkbp:gene |
gptkb:CBX1
|
gptkbp:HGNC_ID |
1552
|
https://www.w3.org/2000/01/rdf-schema#label |
CBX1
|
gptkbp:interactsWith |
gptkb:DNMT1
gptkb:TRIM28 SUV39H1 |
gptkbp:locatedOnChromosome |
17q21.32
|
gptkbp:location |
gptkb:nucleus
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:orthologIn |
CBX1 (mouse)
cbx1a (zebrafish) |
gptkbp:postTranslationalModification |
phosphorylation
sumoylation |
gptkbp:proteinFamily |
chromodomain
chromobox family chromo shadow domain |
gptkbp:relatedTo |
gene silencing
epigenetic regulation chromatin organization |
gptkbp:UniProtID |
Q13185
|
gptkbp:bfsParent |
gptkb:CBX_proteins
|
gptkbp:bfsLayer |
8
|