C1q

GPTKB entity

Statements (26)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName Complement component 1q
gptkbp:associatedWith autoimmune diseases
gptkbp:binds antigen-antibody complexes
gptkbp:component complement system
C1 complex
gptkbp:deficiencyCauses gptkb:systemic_lupus_erythematosus
gptkbp:discoveredIn 1950s
gptkbp:encodedBy C1QA gene
C1QB gene
C1QC gene
gptkbp:formsComplexWith gptkb:C1r
gptkb:C1s
gptkbp:foundIn blood plasma
gptkbp:function initiates classical complement pathway
https://www.w3.org/2000/01/rdf-schema#label C1q
gptkbp:involvedIn innate immunity
gptkbp:location extracellular space
gptkbp:molecularWeight ~460 kDa
gptkbp:recognizedBy C1q receptor
gptkbp:structure hexameric glycoprotein
gptkbp:subunit A chain
B chain
C chain
gptkbp:bfsParent gptkb:CALR
gptkbp:bfsLayer 7