C-reactive protein, pentraxin-related

URI: https://gptkb.org/entity/C-reactive_protein,_pentraxin-related
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy complement system
gptkbp:alsoKnownAs gptkb:CRP
gptkbp:binds phosphocholine
gptkbp:decreasedIn liver failure
gptkbp:discoveredIn 1930
gptkbp:elevatedIn gptkb:autoimmune_disease
gptkb:Bacteria
tissue injury
gptkbp:encodedBy gptkb:CRP_gene
gptkbp:expressedIn liver
gptkbp:foundIn gptkb:human
gptkbp:function marker of inflammation
acute phase reactant
gptkbp:halfLife ~19 hours
gptkbp:inducedBy gptkb:TNF-α
gptkb:IL-1β
gptkb:IL-6
gptkbp:locatedOnChromosome 1q23.2
gptkbp:measures blood
gptkbp:medicalUse diagnosis of infection
monitoring inflammation
gptkbp:memberOf gptkb:pentraxin_family
gptkbp:molecularWeight ~25 kDa (monomer)
gptkbp:notSpecificFor any single disease
gptkbp:OMIM 123260
gptkbp:PDB gptkb:1B09
gptkbp:range <10 mg/L (adults)
gptkbp:structure pentameric
gptkbp:UniProtID gptkb:P02741
gptkbp:usedFor cardiovascular risk assessment
gptkbp:bfsParent gptkb:P02741
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label C-reactive protein, pentraxin-related