|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:biologicalProcess
|
serine/threonine kinase activity
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodedBy
|
gptkb:BUB1B_gene
|
|
gptkbp:fullName
|
gptkb:BUB1_mitotic_checkpoint_serine/threonine_kinase_B
|
|
gptkbp:function
|
mitotic checkpoint regulation
prevents chromosome missegregation
spindle assembly checkpoint
|
|
gptkbp:gene
|
gptkb:BUB1B
|
|
gptkbp:GOID
|
GO:0007094
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BubR1
|
|
gptkbp:interactsWith
|
gptkb:CDC20
gptkb:BUB3
gptkb:MAD2
|
|
gptkbp:involvedIn
|
mitosis
cell cycle
|
|
gptkbp:length
|
1050
|
|
gptkbp:locale
|
gptkb:nucleus
kinetochore
|
|
gptkbp:locatedOnChromosome
|
15q15
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Mosaic_variegated_aneuploidy_syndrome
|
|
gptkbp:OMIM
|
602860
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
2WVI
|
|
gptkbp:phosphorylates
|
gptkb:PLK1
|
|
gptkbp:regulates
|
gptkb:anaphase-promoting_complex/cyclosome_(APC/C)
|
|
gptkbp:UniProtID
|
O60566
|
|
gptkbp:bfsParent
|
gptkb:Anaphase-Promoting_Complex
gptkb:APC_complex
|
|
gptkbp:bfsLayer
|
6
|