Statements (63)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
6
|
| gptkbp:bfsParent |
gptkb:BRM_Racing
|
| gptkbp:alias |
cytochrome P450 2 B6
|
| gptkbp:application |
phase I metabolism
|
| gptkbp:associated_with |
gptkb:psychologist
pharmacokinetics therapeutic drug monitoring biomarker discovery cancer therapy clinical trials drug development autoimmune diseases metabolic syndrome pesticides cardiovascular diseases infectious diseases food additives heavy metals industrial chemicals toxicology studies pharmacodynamics nutritional factors drug metabolism endocrine disorders environmental toxins alcohol metabolism genetic polymorphisms smoking effects |
| gptkbp:clinical_trial |
personalized medicine
adverse drug reactions |
| gptkbp:established |
gptkb:ketoconazole
certain drugs |
| gptkbp:family |
gptkb:API
|
| gptkbp:function |
catalyzes oxidation reactions
|
| https://www.w3.org/2000/01/rdf-schema#label |
BRM P450
|
| gptkbp:interacts_with |
other enzymes
|
| gptkbp:is_a_route_for |
metabolism of fatty acids
|
| gptkbp:is_essential_for |
pharmacogenomics
|
| gptkbp:is_involved_in |
cholesterol metabolism
vitamin D metabolism steroid synthesis eicosanoid synthesis retinoic acid metabolism |
| gptkbp:is_represented_in |
liver
|
| gptkbp:location |
endoplasmic reticulum
|
| gptkbp:material |
gptkb:ibuprofen
gptkb:warfarin gptkb:acetaminophen testosterone caffeine various xenobiotics |
| gptkbp:metabolism |
hydroxylated products
|
| gptkbp:participated_in |
gptkb:rifampicin
some herbal supplements |
| gptkbp:promoter |
CYP family gene
|
| gptkbp:regulatory_compliance |
transcription factors
|
| gptkbp:research |
biomedical studies
|
| gptkbp:role |
detoxification
|
| gptkbp:social_responsibility |
drug-drug interactions
|
| gptkbp:species |
gptkb:Person
|
| gptkbp:theory |
NADPH
|
| gptkbp:was_a_response_to |
monooxygenation
|