|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
BCL-X
BCL2-like 1
BCL2L
|
|
gptkbp:alternativeSplicing
|
produces Bcl-xL isoform
produces Bcl-xS isoform
|
|
gptkbp:associatedWith
|
gptkb:cancer
chemoresistance
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodes
|
Bcl-x protein
|
|
gptkbp:Entrez_Gene_ID
|
598
ENSG00000171552
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
regulation of apoptosis
|
|
gptkbp:HGNC_ID
|
1001
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BCL2L1 gene
|
|
gptkbp:inhibitedBy
|
apoptosis
|
|
gptkbp:interactsWith
|
gptkb:BCL2_protein
gptkb:BAD_protein
BAX protein
BAK protein
|
|
gptkbp:locatedOnChromosome
|
chromosome 20
|
|
gptkbp:memberOf
|
BCL-2 protein family
|
|
gptkbp:mutationAssociatedWith
|
altered apoptosis sensitivity
|
|
gptkbp:OMIM
|
600039
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:product
|
gptkb:Bcl-xL
gptkb:Bcl-xS
|
|
gptkbp:regulates
|
cell survival
histone modification
transcriptional regulation
mitochondrial outer membrane permeabilization
|
|
gptkbp:significance
|
target for cancer therapy
|
|
gptkbp:UniProtID
|
gptkb:Q07817
|
|
gptkbp:bfsParent
|
gptkb:Bcl-xL
gptkb:BCL-XL
|
|
gptkbp:bfsLayer
|
7
|