|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BTB_and_CNC_homology_1,_basic_leucine_zipper_transcription_factor_1
BACH1, transcription factor
|
|
gptkbp:associatedWith
|
cellular senescence
cancer progression
oxidative stress response
|
|
gptkbp:domain
|
gptkb:bZIP_domain
BTB domain
|
|
gptkbp:encodes
|
gptkb:BTB_and_CNC_homology_1_protein
|
|
gptkbp:Entrez_Gene_ID
|
571
ENSG00000019169
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:function
|
repressor of antioxidant response element (ARE)-mediated gene expression
transcription regulator
|
|
gptkbp:gene
|
gptkb:BACH1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
943
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BACH1
|
|
gptkbp:inhibitedBy
|
Nrf2-mediated transcription
|
|
gptkbp:interactsWith
|
gptkb:MafK
gptkb:Nrf2
|
|
gptkbp:involvedIn
|
apoptosis
cell differentiation
cell proliferation
antioxidant defense
tumor metastasis
heme homeostasis
|
|
gptkbp:length
|
736
|
|
gptkbp:locatedOnChromosome
|
chromosome 21
|
|
gptkbp:molecularWeight
|
82 kDa
|
|
gptkbp:mutationAssociatedWith
|
various diseases
|
|
gptkbp:OMIM
|
603299
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Bach1
|
|
gptkbp:proteinFamily
|
gptkb:CNC-bZIP_transcription_factors
|
|
gptkbp:RefSeq
|
NM_006961
NP_008892
|
|
gptkbp:regulates
|
gptkb:Maf_recognition_element_(MARE)
phosphorylation
hemoglobin
oxidative stress
genes involved in iron metabolism
genes involved in oxidative stress
heme oxygenase 1 (HMOX1)
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
O14867
|
|
gptkbp:bfsParent
|
gptkb:FANCJ
|
|
gptkbp:bfsLayer
|
6
|