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gptkbp:instanceOf
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gptkb:gene
|
|
gptkbp:alsoKnownAs
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gptkb:Activity-regulated_cytoskeleton-associated_protein
|
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gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:autism_spectrum_disorder
schizophrenia
|
|
gptkbp:discoveredBy
|
gptkb:Paul_Worley
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodes
|
ARC protein
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
gptkb:long-term_potentiation
memory consolidation
regulation of synaptic plasticity
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Arc gene
|
|
gptkbp:inducedBy
|
neuronal activity
|
|
gptkbp:involvedIn
|
homeostatic synaptic scaling
neuronal communication
|
|
gptkbp:locatedOnChromosome
|
human chromosome 8q24.3
|
|
gptkbp:mRNATransportedTo
|
synapses
dendrites
|
|
gptkbp:mutationAssociatedWith
|
intellectual disability
cognitive deficits
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:product
|
ARC protein
retrovirus-like Gag domain
|
|
gptkbp:proteinForms
|
capsid-like structures
|
|
gptkbp:regulates
|
gptkb:CREB
gptkb:SRF
synaptic strength
MEF2
AMPA receptor trafficking
|
|
gptkbp:relatedTo
|
learning and memory
|
|
gptkbp:studiedIn
|
genetics
molecular biology
neuroscience
|
|
gptkbp:bfsParent
|
gptkb:EGR3
|
|
gptkbp:bfsLayer
|
7
|