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gptkbp:instanceOf
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gptkb:gene
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gptkbp:alsoKnownAs
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gptkb:Activity-regulated_cytoskeleton-associated_protein
|
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gptkbp:associatedWith
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gptkb:Alzheimer's_disease
gptkb:autism_spectrum_disorder
schizophrenia
|
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gptkbp:discoveredBy
|
gptkb:Paul_Worley
|
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gptkbp:discoveredIn
|
1995
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gptkbp:encodes
|
ARC protein
|
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gptkbp:foundIn
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gptkb:Mus_musculus
gptkb:Homo_sapiens
|
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gptkbp:function
|
gptkb:long-term_potentiation
memory consolidation
regulation of synaptic plasticity
|
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gptkbp:inducedBy
|
neuronal activity
|
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gptkbp:involvedIn
|
homeostatic synaptic scaling
neuronal communication
|
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gptkbp:locatedOnChromosome
|
human chromosome 8q24.3
|
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gptkbp:mRNATransportedTo
|
synapses
dendrites
|
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gptkbp:mutationAssociatedWith
|
gptkb:intellectual_disability
cognitive deficits
|
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gptkbp:orthologIn
|
gptkb:mouse
gptkb:right
gptkb:zebrafish
|
|
gptkbp:product
|
ARC protein
retrovirus-like Gag domain
|
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gptkbp:proteinForms
|
capsid-like structures
|
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gptkbp:regulates
|
gptkb:CREB
gptkb:SRF
synaptic strength
MEF2
AMPA receptor trafficking
|
|
gptkbp:relatedTo
|
learning and memory
|
|
gptkbp:studiedIn
|
genetics
molecular biology
neuroscience
|
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gptkbp:bfsParent
|
gptkb:EGR3
|
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gptkbp:bfsLayer
|
7
|
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https://www.w3.org/2000/01/rdf-schema#label
|
Arc gene
|