Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:affects |
cholesterol transport
triglyceride metabolism |
| gptkbp:aminoAcidChange |
Cys112, Cys158
|
| gptkbp:associatedWith |
gptkb:type_III_hyperlipoproteinemia
|
| gptkbp:distinctFrom |
Apolipoprotein E4
Apolipoprotein E3 |
| gptkbp:encodedBy |
gptkb:APOE_gene
|
| gptkbp:foundIn |
humans
|
| gptkbp:function |
binds to lipoprotein receptors
|
| gptkbp:hasIsoform |
Apolipoprotein E4
Apolipoprotein E3 |
| gptkbp:hasPolymorphism |
gptkb:rs7412
|
| gptkbp:hasReducedBindingAffinity |
gptkb:LDL_receptor
|
| gptkbp:involvedIn |
lipid metabolism
|
| gptkbp:isAlleleOf |
APOE*2
|
| gptkbp:molecularWeight |
~34 kDa
|
| gptkbp:presentIn |
gptkb:plasma
lipoproteins |
| gptkbp:significance |
risk factor for dysbetalipoproteinemia
|
| gptkbp:bfsParent |
gptkb:ApoE2
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
Apolipoprotein E2
|