Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:affects |
cholesterol transport
triglyceride metabolism |
gptkbp:aminoAcidChange |
Cys112, Cys158
|
gptkbp:associatedWith |
gptkb:type_III_hyperlipoproteinemia
|
gptkbp:distinctFrom |
Apolipoprotein E4
Apolipoprotein E3 |
gptkbp:encodedBy |
gptkb:APOE_gene
|
gptkbp:foundIn |
humans
|
gptkbp:function |
binds to lipoprotein receptors
|
gptkbp:hasIsoform |
Apolipoprotein E4
Apolipoprotein E3 |
gptkbp:hasPolymorphism |
gptkb:rs7412
|
gptkbp:hasReducedBindingAffinity |
gptkb:LDL_receptor
|
https://www.w3.org/2000/01/rdf-schema#label |
Apolipoprotein E2
|
gptkbp:involvedIn |
lipid metabolism
|
gptkbp:isAlleleOf |
APOE*2
|
gptkbp:molecularWeight |
~34 kDa
|
gptkbp:presentIn |
gptkb:plasma
lipoproteins |
gptkbp:significance |
risk factor for dysbetalipoproteinemia
|
gptkbp:bfsParent |
gptkb:ApoE2
|
gptkbp:bfsLayer |
8
|