|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:canBe
|
prescription only
over-the-counter (rarely)
|
|
gptkbp:combinationTherapy
|
common in HIV treatment
|
|
gptkbp:discoveredBy
|
20th century
|
|
gptkbp:example
|
gptkb:Acyclovir
gptkb:Sofosbuvir
gptkb:Valacyclovir
gptkb:Zidovudine
gptkb:Ribavirin
gptkb:Remdesivir
gptkb:Oseltamivir
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Antiviral
|
|
gptkbp:mechanismOfAction
|
inhibits replication of viruses
|
|
gptkbp:notEffectiveAgainst
|
fungal infections
bacterial infections
parasitic infections
|
|
gptkbp:regulates
|
gptkb:FDA
gptkb:EMA
|
|
gptkbp:researchInterest
|
antiviral resistance
broad-spectrum antivirals
emerging viral diseases
|
|
gptkbp:resistance_can_develop
|
yes
|
|
gptkbp:routeOfAdministration
|
oral
topical
intravenous
|
|
gptkbp:sideEffect
|
nausea
fatigue
headache
liver toxicity
kidney toxicity
|
|
gptkbp:target
|
viral entry
viral assembly
viral enzymes
viral genome replication
viral protein synthesis
viral release
viral uncoating
|
|
gptkbp:usedFor
|
gptkb:herpes_simplex_virus
gptkb:COVID-19
gptkb:hepatitis_C
gptkb:HIV
gptkb:hepatitis_B
influenza
viral infections
|
|
gptkbp:WHO_essential_medicines_list
|
includes some antivirals
|
|
gptkbp:bfsParent
|
gptkb:Cloves
|
|
gptkbp:bfsLayer
|
5
|