|
gptkbp:instanceOf
|
antiviral drug
|
|
gptkbp:administeredBy
|
gptkb:peginterferon_alfa-2a
gptkb:sofosbuvir
gptkb:interferon_alfa
|
|
gptkbp:ATCCode
|
J05AB04
|
|
gptkbp:brand
|
gptkb:Virazole
gptkb:Copegus
gptkb:Rebetol
gptkb:Ribasphere
|
|
gptkbp:CASNumber
|
36791-04-5
|
|
gptkbp:category
|
gptkb:World_Health_Organization_essential_medicines
antiviral drugs
nucleosides
triazoles
|
|
gptkbp:chemicalFormula
|
C8H12N4O5
|
|
gptkbp:contraindication
|
pregnancy
autoimmune hepatitis
severe heart disease
|
|
gptkbp:discoveredBy
|
gptkb:Joseph_T._Witkovski
|
|
gptkbp:discoveredIn
|
1972
|
|
gptkbp:eliminationHalfLife
|
12 days
|
|
gptkbp:excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ribavirin
|
|
gptkbp:KEGGID
|
D00418
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits viral RNA synthesis
|
|
gptkbp:meltingPoint
|
166–168 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
gptkb:X_(US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL418
37542
DB00811
|
|
gptkbp:routeOfAdministration
|
oral
inhalation
intravenous
|
|
gptkbp:sideEffect
|
gptkb:anemia
nausea
fatigue
rash
insomnia
|
|
gptkbp:solubility
|
high
|
|
gptkbp:synonym
|
1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
|
|
gptkbp:UNII
|
49717AWG6K
|
|
gptkbp:usedFor
|
gptkb:hepatitis_C
gptkb:Lassa_fever
gptkb:Crimean-Congo_hemorrhagic_fever
respiratory syncytial virus infection
|
|
gptkbp:bfsParent
|
gptkb:Antiviral
|
|
gptkbp:bfsLayer
|
6
|