Oseltamivir

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf antiviral drug
gptkbp:approvalYear 1999
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode J05AH02
gptkbp:bioavailability 80%
gptkbp:brand gptkb:Tamiflu
gptkbp:CASNumber 196618-13-0
gptkbp:category antiviral drug
prodrug
neuraminidase inhibitor
gptkbp:chemicalFormula C16H28N2O4
gptkbp:contraindication hypersensitivity to oseltamivir
gptkbp:developer gptkb:Gilead_Sciences
gptkbp:discoveredIn 1996
gptkbp:eliminationHalfLife 6-10 hours
gptkbp:excretion renal
gptkbp:firstSynthesized gptkb:Gilead_Sciences
gptkbp:form capsule
oral suspension
https://www.w3.org/2000/01/rdf-schema#label Oseltamivir
gptkbp:indication prophylaxis of influenza
gptkbp:IUPACName ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
gptkbp:KEGGID D08367
gptkbp:legalStatus prescription only
gptkbp:marketedAs gptkb:Roche
gptkbp:mechanismOfAction neuraminidase inhibitor
gptkbp:metabolism hepatic
gptkbp:notEffectiveAgainst gptkb:COVID-19
common cold
gptkbp:patentExpired yes
gptkbp:pregnancyCategory C (US)
B3 (Australia)
gptkbp:prodrugOf oseltamivir carboxylate
gptkbp:PubChem_CID gptkb:CHEMBL123
65028
DB00198
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
vomiting
headache
neuropsychiatric effects
gptkbp:storage room temperature
gptkbp:UNII R7T0KZ6CMO
gptkbp:usedFor treatment of influenza A
treatment of influenza B
gptkbp:WHOModelListOfEssentialMedicines yes
gptkbp:bfsParent gptkb:Influenza_Virus
gptkb:Antiviral
gptkbp:bfsLayer 6