|
gptkbp:instanceOf
|
gptkb:antiretroviral_therapy
gptkb:protease_inhibitor
|
|
gptkbp:administeredBy
|
oral
intravenous
|
|
gptkbp:alsoKnownAs
|
gptkb:AZT
gptkb:Retrovir
|
|
gptkbp:approvalYear
|
1987
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J05AF01
|
|
gptkbp:category
|
gptkb:antiviral_drug
gptkb:WHO_essential_medicine
reverse transcriptase inhibitor
|
|
gptkbp:chemicalFormula
|
C10H13N5O4
|
|
gptkbp:combines
|
gptkb:abacavir
gptkb:lamivudine
gptkb:lopinavir/ritonavir
|
|
gptkbp:developedBy
|
cancer (initially)
|
|
gptkbp:discoveredBy
|
gptkb:Jerome_Horwitz
|
|
gptkbp:discoveredIn
|
1964
|
|
gptkbp:eliminationHalfLife
|
1 hour
|
|
gptkbp:firstHIVUseYear
|
1985
|
|
gptkbp:includedIn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits reverse transcriptase
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
267.24 g/mol
|
|
gptkbp:patentExpired
|
2005
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
gptkb:anemia
gptkb:muscular_dystrophy
nausea
headache
neutropenia
|
|
gptkbp:usedFor
|
HIV/AIDS treatment
|
|
gptkbp:bfsParent
|
gptkb:Antiviral
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
Zidovudine
|