hepatitis C

GPTKB entity

Statements (58)
Predicate Object
gptkbp:instance_of gptkb:disease
gptkbp:caused_by gptkb:hepatitis_C_virus
gptkbp:clinical_trial ongoing for new therapies
gptkbp:community_health significant global health issue
gptkbp:customs associated with drug use
gptkbp:diagnosis blood test
HCV RNA test
anti-HCV antibody test
gptkbp:diseases gptkb:virus
gptkb:HIV
often asymptomatic
can lead to liver cancer
can lead to liver cirrhosis
may resolve spontaneously
can lead to liver failure
requires long-term management
gptkbp:duration 8 to 12 weeks
gptkbp:fibrosis_score used to evaluate liver health
gptkbp:financial_support important for affected individuals
available for treatment adherence
gptkbp:genotype_1 most common genotype in the US
gptkbp:genotype_3 common in South Asia
gptkbp:genotypes six major genotypes
gptkbp:healthcare can be significant for chronic management
https://www.w3.org/2000/01/rdf-schema#label hepatitis C
gptkbp:is_a_resource_for available for support and information
gptkbp:is_vulnerable_to no vaccine available
gptkbp:liver_biopsy used to assess liver damage
gptkbp:liver_cancer_risk increases with chronic infection
gptkbp:liver_disease leading cause of liver transplants
gptkbp:liver_transplant possible for end-stage liver disease
gptkbp:patient_education important for management
gptkbp:prevalence approximately 71 million people infected
gptkbp:prevention screening blood products
avoid sharing needles
gptkbp:provides_guidance_on varies by country
gptkbp:public_awareness aim to reduce stigma
gptkbp:research ongoing for vaccine development
gptkbp:risk_factor intravenous drug use
blood transfusions before 1992
healthcare exposure
tattooing with unsterile equipment
gptkbp:screenings high-risk populations
baby boomers
gptkbp:symptoms fatigue
nausea
abdominal pain
jaundice
gptkbp:transmission blood-to-blood contact
gptkbp:treatment gptkb:glecaprevir/pibrentasvir
gptkb:ledipasvir
gptkb:sofosbuvir
gptkb:velpatasvir
antiviral medications
over 95% with direct-acting antivirals
gptkbp:who_guidelines recommend testing and treatment
gptkbp:bfsParent gptkb:Naomi_Judd
gptkbp:bfsLayer 5