hepatitis C

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:abbreviation HCV infection
gptkbp:affectedPopulation humans
gptkbp:affectsOrgan liver
gptkbp:canBeAcute yes
gptkbp:canBeAsymptomatic yes
gptkbp:canBeChronic yes
gptkbp:canBeCured yes, with modern antivirals
gptkbp:cause end-stage liver disease
gptkbp:causedBy gptkb:hepatitis_C_virus
gptkbp:chronicInfectionRate ~75-85% of cases
gptkbp:complication liver cancer
cirrhosis
liver failure
gptkbp:diagnosedBy HCV RNA test
blood test
liver biopsy
gptkbp:firstDescribed 1989
gptkbp:gene genotype 1
genotype 2
genotype 3
genotype 4
genotype 5
genotype 6
https://www.w3.org/2000/01/rdf-schema#label hepatitis C
gptkbp:ICD-10_code B17.1
B18.2
gptkbp:mortalityRate ~290,000 deaths per year (2022, WHO)
gptkbp:prevalence ~58 million people (2022, WHO)
gptkbp:prevention harm reduction for drug users
no vaccine available
safe injection practices
screening blood products
gptkbp:riskFactor HIV infection
blood transfusion before 1992
hemodialysis
injecting drug use
tattooing with unsterile equipment
gptkbp:symptom nausea
abdominal pain
fatigue
jaundice
loss of appetite
gptkbp:transmissionRoute blood-to-blood contact
mother-to-child transmission
sharing needles
unsafe medical procedures
gptkbp:treatment gptkb:insulin
antiviral drug
direct-acting antivirals
ribavirin
gptkbp:bfsParent gptkb:Francisco_Varela
gptkbp:bfsLayer 4