Antihistamines for systemic use

GPTKB entity

Predicate	Object
gptkbp:instanceOf	Pharmacological class
gptkbp:ATCCode	R06
gptkbp:book	gptkb:Fexofenadine gptkb:Cetirizine gptkb:Loratadine
gptkbp:cause	Sedation Impaired coordination Anticholinergic effects
gptkbp:contraindication	Severe liver impairment Severe renal impairment Hypersensitivity to antihistamines
gptkbp:discoveredIn	1940s
gptkbp:firstBook	gptkb:Diphenhydramine Chlorpheniramine
https://www.w3.org/2000/01/rdf-schema#label	Antihistamines for systemic use
gptkbp:includes	gptkb:Fexofenadine gptkb:Diphenhydramine gptkb:Cetirizine gptkb:Loratadine Chlorpheniramine
gptkbp:interactsWith	gptkb:beer gptkb:CNS_depressants
gptkbp:legalStatus	Prescription and over-the-counter (varies by country)
gptkbp:marketedAs	Multiple pharmaceutical companies
gptkbp:mechanismOfAction	Histamine H1 receptor antagonist
gptkbp:pregnancyCategory	Varies by agent
gptkbp:routeOfAdministration	gptkb:Oral Parenteral
gptkbp:sideEffect	Dizziness Drowsiness Dry mouth
gptkbp:usedFor	gptkb:Urticaria Allergic reactions Allergic rhinitis Pruritus
gptkbp:bfsParent	gptkb:R06AE07
gptkbp:bfsLayer	6