Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:affects |
central nervous system
|
| gptkbp:broadcastOn |
controlled substances (varies by drug)
|
| gptkbp:can_be_abused |
yes
|
| gptkbp:cause |
addiction
confusion drowsiness hypotension respiratory depression bradycardia slurred speech impaired coordination coma (in overdose) death (in overdose) memory impairment |
| gptkbp:contraindicated_with |
other CNS depressants
|
| gptkbp:example |
gptkb:lorazepam
gptkb:diazepam gptkb:zolpidem phenobarbital alprazolam |
| https://www.w3.org/2000/01/rdf-schema#label |
CNS depressants
|
| gptkbp:includes |
gptkb:beer
gptkb:benzodiazepines opioids barbiturates non-benzodiazepine sleep medications |
| gptkbp:interactsWith |
gptkb:beer
opioids antipsychotics antihistamines antidepressants |
| gptkbp:mechanismOfAction |
enhance GABA activity
|
| gptkbp:prescribed_by |
gptkb:physician
|
| gptkbp:regulates |
gptkb:FDA
|
| gptkbp:riskFactor |
tolerance
overdose dependence |
| gptkbp:should_not_be_mixed_with |
gptkb:beer
opioids other sedatives |
| gptkbp:usedFor |
anxiety
muscle relaxation insomnia seizure disorders |
| gptkbp:withdrawal_symptoms |
anxiety
delirium seizures agitation tremors |
| gptkbp:bfsParent |
gptkb:Lyrica
|
| gptkbp:bfsLayer |
5
|