Amyotrophic Lateral Sclerosis
GPTKB entity
Properties (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Psychologist
|
| gptkbp:associated_with |
frontotemporal dementia
primary lateral sclerosis progressive muscular atrophy |
| gptkbp:causedBy |
unknown
|
| gptkbp:clinicalTrials |
ongoing for new treatments
|
| gptkbp:demographics |
2 per 100,000 people
|
| gptkbp:diseaseResistance |
clinical examination
electromyography |
| gptkbp:environmentalImpact |
military service
smoking exposure to toxins |
| gptkbp:events |
gptkb:ALS_Awareness_Month
gptkb:ALS_Ice_Bucket_Challenge |
| gptkbp:famousPerson |
gptkb:Stephen_Hawking
gptkb:Lou_Gehrig |
| gptkbp:famousQuote |
"Life is not over until it is over."
"The only thing I can do is to keep going." "I have lived with the prospect of death for a long time." |
| gptkbp:funding |
increased_after_Ice_Bucket_Challenge
|
| https://www.w3.org/2000/01/rdf-schema#label |
Amyotrophic Lateral Sclerosis
|
| gptkbp:impact |
gptkb:edaravone
motor neurons supportive care financial burden emotional stress riluzole caregiver responsibilities |
| gptkbp:inheritsFrom |
C9orf72 mutations
SOD1 mutations usually between ages 40 and 70 |
| gptkbp:lifespan |
3 to 5 years after diagnosis
|
| gptkbp:provides |
gptkb:ALS_Therapy_Development_Institute
gptkb:ALS_Association gptkb:MDA_(Muscular_Dystrophy_Association) |
| gptkbp:public_perception |
often misunderstood
awareness has increased in recent years associated_with_Lou_Gehrig's_disease |
| gptkbp:research |
ongoing
|
| gptkbp:research_areas |
biomarkers
gene therapy stem cell therapy neuroinflammation neuroprotective strategies |
| gptkbp:symptoms |
respiratory failure
difficulty speaking muscle weakness difficulty swallowing muscle atrophy |